2.A.57.1.10
ENT7 of 417 aas and 11 TMSs, an equilibrative nucleoside transporter in contrast to most plant ENT proteins which are concentrative, functioning by H+ symport (Girke et al. 2015). Binding of purine and pyrimidine nucleosides to the purified recombinant protein, and binding of nucleobases has been demonstrated (Girke et al. 2015).
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| Accession Number: | Q944P0 |
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| Protein Name: | Equilibrative nucleotide transporter 7 |
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| Length: | 417 |
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| Molecular Weight: | 45735.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
Nucleobases, pyrimidine nucleosides, purine nucleosides, H+ |
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1: MTNPEDIPSR IEGKNVARLV CCFLGVGSLV AWNAMLTITD YYYQLFPKYH PSRVLTIVYQ
61: LVANVFIITL ATKEAKLNTR LRNIFGYSLY TAGTFCLIIL DLASHGSGSV VAYVLLCLIV
121: ALFGLADAFV QGAMVGDLSF MSPDFIQAFM AGLGIAGALT SVLRLITKAI FDNSPDGLRK
181: GALLFIGIAT LIELACVFLY TLVFAKLPIV KYYRAKAGKE GAKTVSADLA AAGLQEQAEQ
241: VHQMDESKIQ KLTKKQLLRE NIDLGINLSL IYVVTLSIFP GFLYENTGEH RLGDWYAPVL
301: VAMYNGWDAI SRFIPSIKPL AMESRKWITV CVVARLLLVP AFYFTAKYAD QGWMLFLTSF
361: LGLSNGYLTV CIFSTAPKGY NGPEANALGN LMCVFLLGGI FAGVCLGWLW LIGNDSF