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2.A.57.2.5
High-affinity nucleobase transporter (transports adenine, hypoxanthine, xanthine, guanine, guanosine, allopurinol, and inosine) (Burchmore et al., 2003)

Accession Number:Q86MB6
Protein Name:NBT1
Length:435
Molecular Weight:47653.00
Species:Trypanosoma brucei brucei [5702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Adenine, Hypoxanthine, Xanthine, guanine, Allopurinol, Inosine, Guanosine

Cross database links:

Pfam: PF01733   

Gene Ontology

GO:0016020 C:membrane
GO:0005337 F:nucleoside transmembrane transporter activity
GO:0006810 P:transport

References (1)

[1] “Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan.”  Burchmore R.J.et.al.   12707261

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MALGFSSAGE VYMYATCILL GVSLLMPLNA LVSAPRFMVD YYKYVSGKED SEPNLPFFWK 
61:	NIFTFYNVVS LASQVTAGPT VLTRAARRLP LSVRFALSIT LMMSEVFVVL MMPVIKVPQT 
121:	VAIVLLCLVT IFAGIGKSYH EATCYVLVAS MPSKFMSAVM FGVSLCGVIT STLQCIIKAS 
181:	MEDTYESVLT QSYIYFSLGL LIMAGTLAMA LCLRYNSYAQ EHVAEYRMLK LQEQGVDAES 
241:	QNDENEPVAE GKGEGEGKSE GAMTTAEQLT ATAVMPVARI IRMMLVTVFC GFFLTLFIFP 
301:	SLIIPIDRDH NWFATIAILL YNCGDAIGRF STSFKCVWPP RRALLYATFA RFIFVLPFML 
361:	CIYQYIPGHV GPYIFSFLLG LTNCVGAMSM VYGPITPGLE TAGQKLMAGQ LMGISLLSGI 
421:	AAASVLAMIV VVFLP