2.A.58.1.6
Sodium-dependent phosphate transporter, NaPi-IIA. The stoichiometry is probably 3 Na+ to 1 phosphate molecules. Orthologous to 2.A.58.1.4. Predicted to have 12 TMSs with both the N- and C-termini intracellular (Radanovic et al. 2006). The Km for phosphate is 80 μM (Zhifeng et al. 2012).
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| Accession Number: | H2EJJ3 |
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| Protein Name: | Type IIb Na-dependent phosphate cotransporter |
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| Length: | 671 |
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| Molecular Weight: | 73730.00 |
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| Species: | Sus scrofa (Pig) [9823] |
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| Number of TMSs: | 10 |
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| Substrate |
sodium(1+), phosphate(3-) |
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1: MAPWPEVENA QPNSEDCTPK GTETHKDDTG TPDTKIELQP SHSAMALVEE PPKVEDPWDL
61: PELKNTGIKW SERDTKGKIF CVFQGIGKFI LILVFLYFFV CSLDVLSSAF HLVGGKVAGK
121: FFTSNSIMSN PMSGMVIGVL VTVLIQSSST STSIVVSMVA SSLLTVRSAI PIIMGANIGT
181: SITNTLVALL QAGDRNEFRR AFAGATVHDF FNWLSVLVLL PLEAATGYLE RLTSTVVESF
241: HFKSGEDAPE LLKVITDPFT KLIVQLDKTV LHQIALSDES ARNKSMIKIW CETFTSVMEK
301: NVTVPSPENC TSPSLCWTDG LYTWTMKNIS HKENIAKCKH IFVNFDLPDM VVGTILVITA
361: LLVLCSCRVL MVKVLGSLLK GQVAVVIKKT INTDFPYPFS WVTGYLAILV GTGMTFIVQS
421: SSVFSSTLTP LAGIGVISIE RMYPLMLGAN IGTTTTAILA ALASPGDTLK SALQIALCHF
481: FFNVTGIVLW YPIPFARLPI FLAKWLGNIS SKYRWFAIVY LGFFFFLTPL TVFGLSQAGW
541: PVLVGVGVPI VFLILLVLFI KLLQSRCPRA LPQKLQNWKF LPLWMRSLEP WDKVITALGR
601: CCGKRCCCCC RVCCMLCGCS KCCPCCKCCE DLEEVQDVTV KSPKAFDNPA MDKEAQDGAP
661: RSETVCNITP L