| |
|---|---|
| Accession Number: | P34389 |
| Protein Name: | Niemann-Pick C1 protein homolog 2 |
| Length: | 1274 |
| Molecular Weight: | 142634.00 |
| Species: | Caenorhabditis elegans [6239] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | cholesterol |
Cross database links:
| Entrez Gene ID: | 176165 |
|---|---|
| Pfam: | PF02460 |
| KEGG: | cel:F09G8.4 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0008158
F:hedgehog receptor activity
GO:0042632
P:cholesterol homeostasis
GO:0030301
P:cholesterol transport
GO:0040024
P:dauer larval development
GO:0040025
P:vulval development
| |
References (3)[1] “2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.” Wilson R.et.al. 7906398 | |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MRQGGGGGER MVSVLFLLLI HLALCQAKCV MTECDGEEDS NHPPCKTNKS TYLPITVTRS 61: LNPTYMARFE KYCSYLVQEE DKAQVCCTEL QLKGMTDRIS NAATILGSCP SCFDNFAKLW 121: CQFTCSPDQS KFMKVMETTG PKNVVVKMEF KVNRDFVEGL YESCRHTWFA NGLALRLMSL 181: GGKVSFENFY GFMGTKNLAQ SIPINTEFQF SRMKNAMNIP TTPCHKSAGP KVPACGAIDC 241: PTNAHQLVDI SKVEHLGTKV FHPHFPDFEW LLKICGCLAL TVLLVFILKY SCHRRSAPNG 301: EDGCYVDLGK GNLEVQFEGL CARYANAVIK HPLIFVSLGL IVAAACCSGN FKFHSLTHSV 361: DQVSAADGET RRNEKKFIHS FGPNHRIEQI FINLPPTTKS MFNMPLFEEM FQLVGNIQNL 421: TACYGNSSVK LDDICYKPIG KNHGCAIMSP TNYFQNKWTN FENAGPPTID DEIFDDQHWE 481: HLKYCIRNPL TVSTYSEMSC FGEFSGPIDP ILVFGGSNES IKGAEMYYTA RTIMITVLIR 541: GPEDQAIAWE TAFLNMMSRY EMKHANFTFM TETSVAEEIH TAVETDKIVS VIACAAVLIW 601: VITMLGINHW PESSILSALV HHKLLISISA VMISVISVWC SIGMFSLFGV HATDNAIVVL 661: FFVITCLGIN RIFVIIRTFQ ANGHCYGLPN ISYREMNHRI SNVMRRSIPI VLTNSLICST 721: CLFLAGGVLP YVSVSMPAVE VFARHAGLAI LMDTAFYLLV MLPLFQYDAR REMSGKCEIW 781: PWYELSNESK INLCMEAVDG NLRSPVDWFK LAIAPLLLKK ICRIWIATFF FVSLIIACYC 841: TLCLEFGFNQ VMAFSETSYL TKHFQNMNEN LNIGPPLWFV VEGDVKWHDP KMQNKFCTLA 901: GCDDNSMGNK IRSLAYAENY KGNYLHGDVN IWLDSYLQFM HPRGSCCKMD GKQFCDPSNA 961: THCSSCSSSS VASLTTTEYE FYRNLHHFLE TPPSIQCAHG GMALAKPAIN LTRNGKIQSA 1021: YFSTFFKKLN LSDSIQLYDA WRFAKYLADD IERELEIPGV KVYVYSTFFP YYEQYLTLST 1081: TVYTLVVLVL FVAFVTISLF LRVNLAGSLV TVFVLLSSYL HLMEWMYLLG ITVNVVSVIN 1141: MAMSLGIAVE FFGQMLHGFY NSKKPKREER AFAALVSNGS TTLSGIFPAI MITAGCLSFA 1201: DSRVLITYFC NQLVGIGLVC AVHGVVYMPT LLAIFGSDFY QNVSSEEEST DEAELQDTPP 1261: STTSSTSSTS ETSV