TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
2.A.63.1.1 | Multicomponent K+:H+ antiporter, PhaABCDEFG. Can also transport Na+ (Yamaguchi et al., 2009). | Bacteria |
Pseudomonadota | PhaABCDEFG of Sinorhizobium meliloti |
2.A.63.1.2 | Multicomponent Na+:H+ antiporter, NhaA-G. Nha1,2,3,(4) | Bacteria |
Bacillota | NhaA-G of Bacillus halodurans (strain C-125) NhaA (804 aas)(Q7AJV8) NhaB (146 aas)(Q7AJV9) NhaC (112 aas)(Q7AJW0) NhaD (493 aas)(Q9KD98) NhaE (158 aas)(Q9KD99) NhaF (95 aas)(Q9KDA0) NhaG (117 aas)(Q9KDA1) |
2.A.63.1.3 | Multicomponent Na+:H+ antiporter, MnhABCDEFG | Bacteria |
Bacillota | MnhABCDEFG of Staphylococcus aureus |
2.A.63.1.4 | Multicomponent Na+:H+ antiporter, MrpA-G (ShaA-G) (all components comprise a multi-component complex) (Kajiyama et al., 2007; Morino et al., 2008). The MrpA, MrpB, and MrpD subunits contain membrane-embedded and essential acidic residues (Kajiyama et al. 2009). Several residues important for Na+/H+ antiport activity, sodium exclusion, individual Mrp protein levels, or Mrp complex formation have been identified (Morino et al., 2010). | Bacteria |
Bacillota | MrpA-G of Bacillus subtilis MrpA (801 aas; Q9K2S2) MrpB (143 aas; O05259) MrpC (113 aas; O05260) MrpD (493 aas; O05229) MrpE (158 aas; Q7WY60) MrpF (94 aas; O05228) MrpG (124 aas; O05227) |
2.A.63.1.5 | Putative membrane protein | Bacteria |
Actinomycetota | Putative membrane protein of Streptomyces coelicolor |
2.A.63.2.1 | The Na+:H+ antiporter, MrpA-G complex. Catalyzes Na+:H+ and Li+:H+ antiport. The MrpB subunit may have this transport activity by itself (Fukaya et al., 2009). | Bacteria |
Cyanobacteriota | MrpA-G of Aphanothece halophytica MrpA (C7G3J5) MrpB (C7G3J6) MrpC (C7G3I9) MrpD1 (C7G3J0) MrpD2 (C7G3J1) MrpE (C7G3J2) MrpF (C7G3J3) MrpG (C7G3J4) |