Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.75.1.1
D- and L-lysine, L-histidine and L-arginine exporter (LysE) (Stäbler et al. 2011).  The system may also export L-citrulline (Lubitz et al. 2016).

Accession Number:P94633
Protein Name:LysE aka CGL1262
Length:233
Molecular Weight:25082.00
Species:Corynebacterium glutamicum (Brevibacterium flavum) [1718]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate lysine, L-citrulline, arginine, histidine

Cross database links:

RefSeq: NP_600485.1    YP_225551.1   
Entrez Gene ID: 1019244    3343730   
Pfam: PF01810   
BioCyc: CGLU196627:CG1424-MONOMER   
KEGG: cgb:cg1424    cgl:NCgl1214   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006865 P:amino acid transport

References (2)

[1] “A new type of transporter with a new type of cellular function: L-lysine export from Corynebacterium glutamicum.”  Vrljic M.M.et.al.   8971704
[2] “The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.”  Kalinowski J.et.al.   12948626

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MEIFITGLLL GASLLLSIGP QNVLVIKQGI KREGLIAVLL VCLISDVFLF IAGTLGVDLL 
61:	SNAAPIVLDI MRWGGIAYLL WFAVMAAKDA MTNKVEAPQI IEETEPTVPD DTPLGGSAVA 
121:	TDTRNRVRVE VSVDKQRVWV KPMLMAIVLT WLNPNAYLDA FVFIGGVGAQ YGDTGRWIFA 
181:	AGAFAASLIW FPLVGFGAAA LSRPLSSPKV WRWINVVVAV VMTALAIKLM LMG