TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.80.1.1









The tricarboxylate transporter, TctABC (Somers and Kay 1983; Winnen et al. 2003).  The high resolution structure of the receptor, TctC, is known (Sweet et al. 1984).

Bacteria
Proteobacteria
TctABC of Salmonella enterica
TctA (M, 12 TMS)
TctB (M, 4 TMS)
TctC (R)
2.A.80.1.2









Terephthalate (TPA) aromatic acid uptake transport system, TpiBA/TphC (Hosaka et al. 2013).  May transport several aromatic acids including isophthalate, o-phthalate and protocatechuate.  Consists of three subunits: TpiB (503 aas and 13 TMSs), TpiA (162 aas and 4-5 TMSs) and TphC (322 aas and 1 TMS. tpiAB comprise an operon while tphC maps elsewhere.  o-phthalate and protocatecuate may use other receptors (Hosaka et al. 2013).

Bacteria
Proteobacteria
TpiBA/TphC of Comamonas sp. strain E6
TpiB (M, large) (S6BBY9)
TpiA (M, small) (S6CBZ0)
TphC (R)
2.A.80.1.3









The putative tricarboxylic acid transporter, TctABC.  This organism is claimed to have 66 TCT family members (Ma et al. 2009).  The organism utilizes many aromatic and non-aromatic acids that could be substrates of these transporters. 

Bacteria
Proteobacteria
TctABC of Comamonas testosteroni
TctA (M, large) (D0J0R9)
TctB (M, small) (D0J2J4)
TctC (R) (D0J060)
2.A.80.1.4









Pmf-dependent citrate uptake porter, TctABC (Brocker et al. 2009).

Bacteria
Actinobacteria
TctABC of Corynebacterium glutamicum
TctA (M, large; 510 aas) (S5Y5N9)
TctB (M, small; 188 aas) (S5XH28)
TctC (R) (334 aas) (S5XTE7)
2.A.80.2.1









TctA homologue; 12 TMSs; DUF112

Archaea
Euryarchaeota
TctA homologue of Methanosarcina mazei
2.A.80.2.2









TctA homologue, 12 TMSs; DUF112

Archaea
Euryarchaeota
TctA homologue of Archeoglobus fulgidus