Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.81.2.1
Homologue of AspT (384 aas; 12 putative TMSs; with potential membrane embedded loops between TMSs 5 and 6 and TMSs 11 and 12 (the two halves are internally duplicated). The central hydrophilic domain in 2.A.81.1.1 is absent in this homologue. Although the experimentally predicted topology for 2.A.81.1.1 differs from this prediction, we consider it possible that the experimentally determined topology is in error (M. Saier, unpublished observations).

Accession Number:O52005
Protein Name:AspT homologue
Length:384
Molecular Weight:39531.00
Species:Halobacterium salinarium [2242]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-aspartate(1-)

Cross database links:

RefSeq: NP_046046.1   
Entrez Gene ID: 1446880   
Pfam: PF06826   
BioCyc: HSP64091:H1224-MONOMER   

References (2)

[1] “Genome sequence of Halobacterium species NRC-1.”  Ng W.V.et.al.   11016950
[2] “Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid or minichromosome?”  Ng W.V.et.al.   9847077

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MAFIDTLVGS GVFVMFLAVV VGMAFGRINF GRGIKFGVAG PLFAGLVLGH FGFTVPDAYS 
61:	GLTLALFVAA VGLIAAHEIE GTVKTYGLNF IAISVLMPTI AAILTYVWVV VVFPNASTGL 
121:	IMGSFSGALT SSPGLGSAIE ALPEAAAQQY QIGHSVGYVI GVLIIVMFQQ LYPKLSGMNL 
181:	DAEKQQFSEK VSDIAENANI EVVTFSVLGF ALVLATGTVL GSIPIPLGPI GVITLGTTGG 
241:	VLITALVLGY LGKIGPVTMR METTILSEIR AFTLAMFLAV VGIDAGSGLV ETIAEYGVEI 
301:	VVTAGLNSIV AIIGGLVLTR VIWKMDWIHA AGGITGGHTD TKGLAAAIDA TGADEVAAGY 
361:	GNTYPFALLA MVIYAKILVA VIPL