TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
2.A.94.1.1









Putative phosphate transporter, Pho1 (one of ten paralogues) (782 aas; 10 or 11 TMSs) (Hamburger et al., 2002)

Eukaryota
Viridiplantae
Pho1 of Arabidopsis thaliana (Q8S403)
2.A.94.1.2









Xenotropic and polytropic murine-leukemia virus receptor Xpr1 of 671 aas and 11 or 12 TMSs.

Eukaryota
Metazoa
Xpr1 of Culex pipiens (XP_001850310)
2.A.94.1.3









Pho1 homologue of 396 aas and probably either 10 or 11 TMSs, ERD1.

Eukaryota
Fungi
ERD1 of Cercospora beticola
2.A.94.1.4









EXS-domain-containing protein of 565 aas and probably 10 or 11 TMSs.

Eukaryota
Fungi
EXS protein of Mortierella elongata
2.A.94.1.5









EXS family protein of 414 aas and 8 - 11 TMSs.

Eukaryota
Ciliophora
EXS protein of Tetrahymena thermophila
2.A.94.1.6









The Xenotropic and polytropic retrovirus receptor 1, the XPR1 or SLC53A1 protein, also called SYG1 or XR. XPR1 exports inorganic phosphate in metazoans (Giovannini et al. 2013) and is associated with Primary Familial Brain Calcification (PFBC, formerly known as Fahr disease or Idiopathic Basal Ganglia Calcification in idiopathic forms) (Legati et al. 2015 and Anheim et al. 2016). It binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7), important intracellular signaling molecules (Wild et al. 2016).

Eukaryota
Opisthokonta
XPR1 of Homo sapiens