3.A.1.204.44
Drug resistance ABC exporter, NpABC2, of 1092 aas and 8 - 10 TMSs in a 1 (N-terminus) + 1 + 6 - 8 TMS (C-terminus) arrangement. NpABC2 plays a role in the drug resistance of N. parvum and affects its virulence (Chen et al. 2022).
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| Accession Number: | R1GEL2 |
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| Protein Name: | Putative abc transporter protein |
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| Length: | 1094 |
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| Molecular Weight: | 120408.00 |
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| Species: | Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus) [1287680] |
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| Number of TMSs: | 9 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
drug |
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1: MRSPRWAAPI LAAAAAFSSV AAAQRTFANY TSNDLQDPFS VYDDRPDGCP PCFNCNLEQF
61: PCHQFAPCSK SNGRCVCPPG FGGNDCSDPV CGSLADGRDR APREGDSCNC KEGWTGINCN
121: VCTSNQACNA LMPEGVDGVC YREGLVVKEN YQMCDITNRK ILDQLKDQKP QATFSCNTET
181: EECNFQFWVD QKESFYCGLD TCGFTVLQES NRNTTKYRCE NVKCSCIPGR MLCGEEGSID
241: IGEFLDESIK GPATFKTVST EGGSSEDGSL FSEPAMNDLI ASVFGDESIT LRCHSGECLH
301: ETEIPGYERP VKTINTPLIA GVIAGCALFI VAVILLVWIL SRRSAARGWG PIHLTDDEDD
361: EAAKLIADHK PAALHFENVS YQLSGKQILT NIQGAVRPGE LMAIMGASGA GKTTFLDILA
421: RKNKRGSVYG DIYVNGEKIP NDDFRSVIGF VDQEDALLPT LTVHETIMDS ALLRLPKEMS
481: RGAKEQRVDD IEKQLGIYHI RHQIIGSEEG NGRGISGGEK RRVGIACELV TSPSILFLDE
541: PTSGLDAYNA FNVVECLVNL VKTYNRTVVF TIHQPRSNIV ALFDQLILLA KGRTVYSGPF
601: ADCQAYFDKV GYPCPPGFNI ADFLVDLTMH ASTPRRPIDE DSSLFAPRDD IPTRASSAMG
661: VKSIPSISNA SIEEGRPDAP SESASNRPKN KRRTSIRQQQ ERQLFTRKKS GYEQPQTPKT
721: DDESIADTER DNIRLHRQQG APPPQILEDP DQLPPAAEGY TGTDLDTLVS SYSRSDVAEA
781: LHEDIYTTIM GAHTANGHAD SGAANGNGYK VKGFRKVGIF SQFIILSKRT WRNLYRNPLL
841: MLTHYAIAIV LAVLIGYLFY GLTDDIKGFQ NRLGLFFFLL ALFAFSTLTS LSVFAPERLI
901: FTRERAKGYY KPLAYFSAKV LFDIIPLRLI PPIIMGAIVY PMTGLIPAAA EFWKFMLFLT
961: LFNLAAANIC LFIGIVVKNQ GVANLIATLV MLFSLLFGGF LLNHETIPKS ALWLQTLSIF
1021: HYGFEGLIVN EVKYLSLVDH KYGLDIEVPG SAILSSFGFN VLALWHDAIG LAIFCGVFIV
1081: LAYASMHLLL VETR