3.A.3.10.15
This protein was previously designated the functionally uncharacterized P-type ATPase 19 (FUPA19 of 1807 aas) (Thever and Saier 2009). The unusually large size and number of TMSs is unique to this protein. Whether this is a consequence of an artifact of sequencing is not known. It may be a Mn2+-ATPase (by similarity).
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| Accession Number: | I7MI73 |
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| Protein Name: | E1-E2 ATPase family protein |
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| Length: | 1807 |
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| Molecular Weight: | 207357.00 |
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| Species: | Tetrahymena thermophila (strain SB210) [312017] |
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| Number of TMSs: | 16 |
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| Substrate |
manganese(2+) |
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1: MGKQQKLFLY KKKQGLISKT QASKKSQIQQ KENIIEQNRV MDEQELKING QIKIINSQIE
61: GECYIQEVYA LKQQQYKQFL VILLNIITFG GYYLLENWYE RSLLKLRYCY TDDIKQATHF
121: LIVQLDNTFQ IVKHFEIQLQ SAISFDNRFL RYIYSEEEKY FKCIHFNYTN FLEKNQLGRK
181: GLNQQQLQLL EQCYGKCIMQ IPIPSYWSYL HKELINPFFM FQIFSVCIWA YDDYYAFCIA
241: ITLILSISTA SNICQIRSNL ASFTKIAFYE TEIMIKRDKI EKQTSSNILP GDLFYINDQM
301: KVPCDCILIQ GQALVNEASL TGESVPVLKY NYEFNEEVDK KCILYEGTSV IQIQNNTSEH
361: GCLALAIRTG FTTHRGQLVR SILFPRPHSF KFYEESIKFL KFLFALTFVA FAILLPRLYQ
421: TMELHYIALK LTDLLTVTVP PSLPFALQVG VVFSMQMLKQ KKIYCINSEK VVVGGRVDTV
481: VFDKTGTLTE DRMDLKGFLP IDDNGNFFKN ELVKEDILNV FQKENTQHIS KSMQISLNCM
541: GSCHSIMIRK NQQCSPKQDA LQNNYKNHLI GDPMEIQLLN ISGCKLYANG DISSSFGQQF
601: KIIKTLEFSS ERQKMTVICE DKSELIQENK FLYVFSKGAP EAIHKICNNY PKNYNKMLDK
661: YTQEGLRVLS LAYKKLPFSL ISQFQQNSSQ NTDQNNSNVN TNNLQPESIE SEMNFLGFVF
721: FENPLKEATA QTLQQLKEAK INIIMATGDN PQTALSVGEK CHFFDFEDNV TFINLAQLGN
781: NKRLTLTNSK FNTYAEVSEV DELDEYLSDE LSSFNSTDSQ ENKDQSEQPF GKDKEQLKLL
841: KSLKQAEELN SQGRPRDLIS KNENDERKKL SNKESSQVDD IELKDNILIQ QKSSGNKSQT
901: KDILNGEIKQ KCKVNEKQDQ LYICDKNSTT SSSQKIGDES IDIENDQQLN KQSNSNSSED
961: LKEEPDSLHL PISQYVLDSF IREALNQKSE GFVMNGAVFD EIYFKGEIND LSLMLLEKTR
1021: IFARMKPNHK TYLVELLQKR AVAMVGDGAN DCGALKQADI GLALSQLEAS ISAPFSGECI
1081: SNIIEVLIQC RAGLKTAFNN FNFIAMYSIV QFTTTTILYY CFSMQSDLQL LYIDILVVSS
1141: LILTMGTTNQ LSNINSMTSA SNKLSMQLPD QSLISLKNML SLGGHTLLNI ITQLVILFLL
1201: SKQSFFEGIE ANKQFYEKED IMTWNSSEVS TLFLFSNFIY LALSICYSDG KPFKNNFYTN
1261: KLFICNFMVL LAYCIQMCLV PSLNYYYFYI NTSMSFSWCS FMCIAGIGYI LLSYFYENTL
1321: LANSEGNSIQ NLVYYLLEAF FFVSAAPLAI MSDNVLIISA CLLVQLMFYI IVIAALQFFA
1381: SNIFLQSILF GRLLVMMKNW YSNKKLVLCV GLTYFLNEFF SILTVYWDQG IANQGLIIQG
1441: KPSIMGLSIV NEDDEGQQDQ SEANQEQKKE KHQNQQGGII QNVWGLNQSF VKKVYEDDND
1501: APKINFFKQL PQLKHLLFFF ISSICLKLFD WYTRNQLLGS LQPFIDQQDF SKYIFYLGMF
1561: GLGGIGGIVA LGIILDVRNQ EFTLRMAICS AIGLSISYIS SLLYYYGIIP QLAYEILVGA
1621: FEFSFYCTYQ VGVPIVLVFD LLRYGDFSYL IIPIFSALDR IVNALFNIFN KEPQNWTDSS
1681: TVVQPLCISL MFLSLMIQYL KDRQRSSKNF QEQLDEDDED EVQGKNTNNL LSEILEDRKG
1741: DGDQSNLNRS TSKNLTKNNF KIQISSDDAL SQDIHEHQFK NSLEQDTKFV IEKRNVSLKD
1801: NISSDFE