3.A.3.2.46
Ca2+-ATPase of 880 aas and 10 TMSs, Ca1. Key intermediates have been identified; Ca2+ efflux is rate-limited by phosphoenzyme formation. The transport process involves reversible steps and an irreversible step that follows release of ADP and extracellular release of Ca2+ (Dyla et al. 2017).
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| Accession Number: | GAT39076.1 |
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| Protein Name: | GAT39076.1 ATPase [Listeria monocytogenes] |
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| Length: | 881 |
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| Molecular Weight: | |
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| Species: | Listeria monocytogenes [1639] |
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| Number of TMSs: | 9 |
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| Substrate |
calcium ion |
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1: MEIYRKSAAE TFTQLEATEQ GLTTSEVTKR QEKYGFNELK NKKKDPLWKL FLETFKDPMV
61: IVLVVAALVQ LVLGEVVESL IIFLVLIVNS IISVVQTRKA ESSLDALREM SAPVAKVIRD
121: GSKQSIHARE LVPGDVVILD AGDFVPADGR LFESGSLKID EGMLTGESEA VEKYIDTIPD
181: EVGLGDRVNM VFSGSLVVYG RGMFVVTGTA SETEIGKIAG LLETAEAKQT PLQRKLESFS
241: KKLGLGILAL CVLIFAVEAG RVLLGDNSAD MATAILNAFM FAVAVAVAAI PEALSSIVTI
301: VLAVGTNKMA KQHAIIRKLP AVETLGSTSV ICTDKTGTLT QNKMTVVDYY LPDGTKENFP
361: ESPENWSEGE RRLIHIAVLC NDSNINSEGK ELGDPTEVAL IAFSNKNNQD YNEIREKFIR
421: EGEIPFDSDR KLMSTLHTFN ENKAMLTKGG PDVMFARCSY VFLDGEEKPM TEEILAKLKE
481: TNEEFSNQAL RVLAYGYKRM PADTTELKLE DEQDIVLVGL TAMIDPPREA VYASIEESKK
541: AGIRTVMITG DHKTTAQAIG RDIGLMDADD IALTGQELDA MPEEELDKKL EHIAVYARVS
601: PENKIRIVKA WQKKGKITAM TGDGVNDAPA LKQADIGVAM GSGTDVAKDS AAMILTDDNF
661: VSIVDAVGVG RTVFDNIKKS IAYLFAGNLG AIIAILFALV LDWINPFTAL QLLFINLVND
721: SLPAIALGME KAEPDVMKRK PRDINEGIFA GGTMRAVISR GVLIGIAVII SQYIGLQISP
781: EMSVAMAFTT LILARTLQTF AARSNVQTAF GAGFFSNKYV IGAVLLCFVL YGITVLPGAR
841: EIFSIPASFG LHEWSIAAGL ALAAVVMMEI IKLVQNKFFK