TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
4.B.1.1.1









The (putative) ATP-dependent, NMN synthesizing, nicotinamide nucleoside phosphorylating, group translocator, PnuC/NadR

Bacteria
Pseudomonadota
PnuC/NadR of Salmonella typhimurium
PnuC (P24520)
NadR (AAL23395)
4.B.1.1.2









The (putative) ATP-dependent nicotinamide nucleoside phosphorylating group translocator, PnuC/NadR
Bacteria
Pseudomonadota
PnuC/NadR of Haemophilus influenzae
PnuC (AAX88086)
NadR (P44308)
4.B.1.1.3









PnuC homologoue (214aas; 6 TMSs?)

Bacteria
Actinomycetota
PnuC homologue of Streptomyces coelicolor (Q9EWJ7)
4.B.1.1.4









The putative thiamin porter, PnuT. Some PnuT homologs may use a facilitated diffusion mechanism for thiamine uptake (Jaehme et al. 2018). Synthesis of the system is regulated by a TPP riboswitch (Rodionov et al. 2002).

Bacteria
Pseudomonadota
PnuT of Shewanella oneidensis (Q8EDN0)
4.B.1.1.5









Riboflavin porter, PnuX. Regulated by FMN riboswitch (Vitreschak et al. 2002). PnuX was biochemically characterized (Vogl et al. 2007). Transport by PnuX was not energy dependent and had high apparent affinity for riboflavin (K(m) 11 microM).

Bacteria
Actinomycetota
PnuX of Corynebacterium glutamicum (Q8NU75)
4.B.1.1.6









The putative deoxynucleoside porter, PnuN. Regulated by NrdR repressor (Rodionov and Gelfand 2005)

Bacteria
Bacillota
PnuN of Enterococcus faecalis (Q837U1)
4.B.1.1.7









Putative nicotinamine riboside transporter, PnuC of 409 aas and 9 TMSs in a 1 + 8 TMS arrangement with an N-terminal hydrophilic domain.

Bacteria
Bacillota
PnuC of Faecalitalea cylindroides
4.B.1.1.8









Putative nicotinamide mononucleotide transporter of 228 aas and 8 TMSs in a 4 + 4 TMS arrangement.

Viruses
Heunggongvirae, Uroviricota
PnuC homologue of Bacillus phage PBC2
4.B.1.2.1









PnuC homolgoue (239aas, 8 TMSs) (TMSs 1-8 exhibit sequence similarity with TMSs 1-8 of 2.A.3.8.13).

Bacteria
Bacillota
PnuC homologue of Lactobacillus antri (C8P3X6)