TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.106.1.1









Caltrin of 80 aas and 1 N-terminal TMS.  Caltrin (calcium transport inhibitor) is a family of small, basic proteins of the mammalian seminal plasma which bind to sperm cells during ejaculation and inhibit the extracellular Ca2+ uptake, preventing the premature acrosomal exocytosis and hyperactivation when sperm cells ascend through the female reproductive tract (Grasso and Coronel 2017). It binds calmodullin but not calcium.  It also inhibits the growth of microorganisms, possibly by acting as an antibiotic, permeabilizing the bacterial membrane (Krauhs et al. 1990).

Eukaryota
Metazoa
Caltrin of Bos taurus (Bovine)
8.A.106.1.2









caltrin isoform X2 of 117 aas and 1 TMS

Eukaryota
Metazoa
Caltrin X2 of Ovis aries musimon
8.A.106.2.1









Peptide YYA precursor of 97 aas and 1 N-terminal TMS.  Peptide YY (PYY) influences appetite suppression and body weight, probably through interaction of PYY with hypothalamic Y2 receptors (Lafferty et al. 2018).

Eukaryota
Metazoa
PYY of Danio rerio
8.A.106.2.2









Goannatyrotoxin-Vere1 of 99 aas and 1 N-terminal TMS (Fry et al. 2010). 

Eukaryota
Metazoa
Goannatyrotoxin-Vere1 from the venom of Varanus eremius (the Pygmy desert monitor lizard)