8.A.107.1.3
AC45 or ATP6AP1 chaparone protein of the V-type ATPase (Schoonderwoert and Martens 2002). ATP6AP2 mutations impair protein stability and the interaction with ATP6AP1, a constituent of the V0-ATPase assembly complex. Missense mutations in ATP6AP2 lead to impaired V-ATPase assembly and subsequent defects in glycosylation and autophagy (Rujano et al. 2017).
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| Accession Number: | Q7JR49 |
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| Protein Name: | LD09158p |
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| Length: | 379 |
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| Molecular Weight: | 41124.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MLWKSLIALC VIGAAVAEQT PVFLWGANSV AKPSLKTVSQ VEFAEQLAAL LEDHMVVAFE
61: ENGLSSKDFL CSNSQAQSCY AQLQGVSPKT YYTSVENPSE ALRSVAAKRE HNSIDASGKL
121: TTPAKCAVGT ALFVTFEDAA ESREASLESH DAAIAAISKQ FECKVAYLYL AAPSTAPVVQ
181: RRTRRDTAAT TGGIMWKSTN QFQIFYTALL YNGNPITVTD LKLTNSSSTK LSVVMDTSVA
241: DKPITFDVVY NGGYFSLSNL VYDNNNFRSS GVNAPTTFSY SCGNLTLESA AVNNMYNTLS
301: FKSLQLQAPF DGTYKEDFPF GDSWDCVGFV TPGILMGLFV VALLLVIMFV GVCWMMDINT
361: MDRFDDPKGK TITINAAAE