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8.A.116.1.1
The transmembrane inner ear expressed protein, Tmie (153aas; 2 TMSs).  Hair cells express two molecularly and functionally distinct mechanotransduction channels with different subcellular distributions. One is activated by sound and is responsible for sensory transduction. This sensory transduction channel is expressed in hair cell stereocilia, and its activity is affected by mutations in the genes encoding the transmembrane proteins TMHS (TC# 1.A.82.1.1), TMIE (this family), TMC1 and TMC2 (family 1.A.17.4) (Wu et al. 2017). The other is the Piezo2 channel (TC# 1.A.75.1.2) (Qiu and Müller 2018).

Accession Number:Q8K467
Protein Name:Transmembrane inner ear expressed protein
Length:153
Molecular Weight:17027.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type I membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAGRQHGSGR LWALGGAALG ACLAGVATQL VEPSTAPPKP KPPPLTKETV VFWDMRLWHV 
61:	VGIFSLFVLS IIITLCCVFN CRVPRTRKEI EARYLQRKAA KMYTDKLETV PPLNELTEIP 
121:	GEDKKKKKKD SVDTVAIKVE EDEKNEAKKK GEK