TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.126.1.1









The human nuclear receptor coactivator 7 (NCOA7) of 942 aas.  It inhibits the V-type ATPase and therefore has multiple consequences, including inhibiting viral entry into vesicles; see family description (Doyle et al. 2018).

Eukaryota
Metazoa, Chordata
NOCOA7 of Homo sapiens
8.A.126.1.2









GTPase-activating protein (GAP), skywalker (Sky) of 587 aas, for Rab35 which regulates synaptic vesicle (SV) protein recycling and turnover at neuromuscular junctions (Uytterhoeven et al. 2011). The N-terminal domain of this protein show sequence similarity with family 8.A.87, but the C-terminal domain shows greater seqence similarity with 8.A.116.1.1.

Eukaryota
Metazoa, Arthropoda

GAP of Drosophila melanogaster (Fruit fly)
8.A.126.1.3









TBC1 domain family member 24 isoform X1 of 655 aas and 2 C-terminal TMSs.

Eukaryota
Metazoa, Chordata
TBC1 protein of Marmota flaviventris
8.A.126.1.4









Uncharacterized TLD family protein of 484 aas and 2 TMSs near the N-terminal domain.

UP of Trichomonas vaginalis