| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.141.1.1 | Eros chaparone protein of 468 aas and one N-terminal TMS. In response to extracellular ATP, the purinergic receptor P2X7 (1.A.7.1.3) mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1beta production. Eros in mice is absolutely required for P2X7 function in all of these capacities. It probably functions as a chaparone protein for the insertion and assembly of this system as well as others (Ryoden et al. 2020). | Eukaryota |
Metazoa, Chordata | Eros of Homo sapiens |
|
8.A.141.1.2 | Endoplasmic reticulum oxidoreductins 2, Ero2, of 479 aas and 1 N-terminal TMS. | Eukaryota |
Viridiplantae, Streptophyta | Ero2 of Arabidopsis thaliana (Mouse-ear cress) |
|
8.A.141.1.3 | Endoplasmic reticulum oxidoreductin, putative of 469 aas and 2 TMSs, N- and C-terminal, with up to four additional possible TMSs, hydrophobic peaks that may or may not be TMSs. | Eukaryota |
Apicomplexa | Eros of Plasmodium vinckei petteri |
|
8.A.141.1.4 | AERO1 of 333 aas and at least two TMSs, N- and C-terminal, and possibly more in between, based on hydrophathy plots. | Eukaryota |
Fungi, Microsporidia | AERO1 of Enterocytozoon hepatopenaei |
|
8.A.141.1.5 | Uncharacterized protein of 295 aas with 2 TMSs, N- and C-terminal. Possibly oxidoreductase, acting on a sulfur group of donors and a disulfide as acceptor (InterPro). | Eukaryota |
Haptophyta | UP of Emiliania huxleyi (Pontosphaera huxleyi) |