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8.A.16.1.1
Calcium channel γ1-subunit, CACNG1 of 222 aas and 4 TMSs.  Evolution of the family of gamma subunits has been presented and discussed (Burgess et al. 2001). Mutations in genes encoding proteins involved in ion channel function (including CACNG1) may be responsible for the aggressive behavior of a tumor (Sharma et al. 2019).

Accession Number:Q06432
Protein Name:CACNG1 aka CACNLG
Length:222
Molecular Weight:25028.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

RefSeq: NP_000718.1   
Entrez Gene ID: 786   
Pfam: PF00822   
OMIM: 114209  gene
KEGG: hsa:786   

Gene Ontology

GO:0005891 C:voltage-gated calcium channel complex
GO:0015270 F:dihydropyridine-sensitive calcium channel a...
GO:0006816 P:calcium ion transport
GO:0006936 P:muscle contraction

References (4)

[1] “Molecular characterization of the gene encoding the gamma subunit of the human skeletal muscle 1,4-dihydropyridine-sensitive Ca2+ channel (CACNLG), cDNA sequence, gene structure, and chromosomal location.”  Powers P.A.et.al.   8387489
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Localization of the gamma-subunit of the skeletal muscle L-type voltage-dependent calcium channel gene (CACNLG) to human chromosome band 17q24 by in situ hybridization and identification of a polymorphic repetitive DNA sequence at the gene locus.”  Iles D.E.et.al.   8404045

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSQTKMLKVR VTLFCILAGI VLAMTAVVTD HWAVLSPHME HHNTTCEAAH FGLWRICTKR 
61:	IPMDDSKTCG PITLPGEKNC SYFRHFNPGE SSEIFEFTTQ KEYSISAAAI AIFSLGFIIL 
121:	GSLCVLLSLG KKRDYLLRPA SMFYAFAGLC ILVSVEVMRQ SVKRMIDSED TVWIEYYYSW 
181:	SFACACAAFI LLFLGGLALL LFSLPRMPRN PWESCMDAEP EH