| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.162.1.1 | Cereblon, CRBN, of 442 aas and 0, 1, or 2 TMSs. See family description for function. CRBN determines HSP90 activity toward transmembrane proteins (Heider et al. 2021). | Eukaryota |
Metazoa, Chordata | CRBN of Homo sapiens |
|
8.A.162.1.2 | Uncharacterized protein of 518 aas. | Eukaryota |
Viridiplantae, Chlorophyta | UP of Dunaliella salina |
|
8.A.162.1.3 | Uncharacterized protein of 157 aas and 0 or 1 TMS. | Bacteria |
Thermodesulfobacteriota | UP of Desulfohalobium retbaense |
|
8.A.162.1.4 | LON peptidase substrate-binding domain-containing protein of 233 aas and one N-terminal TMS. | Bacteria |
Actinomycetota | Lon domain of Actinocatenispora thailandica |
|
8.A.162.1.5 | Protein cereblon isoform X1 of 183 aas and possibly 2 TMSs, one at the N-terminus and one near the C-terminus of the protein. | Eukaryota |
Metazoa, Mollusca | Cereblon of Octopus sinensis |
|
8.A.162.1.6 | Uncharacterized protein of 121 aas and possibly one TMS. | Bacteria |
Spirochaetota | UP of Leptospira sarikeiensis |
|
8.A.162.1.7 | Uncharacterized protein of 181 aas and 1 N-terminal TMS. | Eukaryota |
Metazoa, Chordata | UP of Scleropages formosus |
|
8.A.162.1.8 | Peptidase S16 of 231 aas and 1 N-terminal TMS plus two additional possible TMSs, that might be within two sequential repeat units. | Bacteria |
Pseudomonadota | Peptidase S16 of α-proteobacteria bacterium PA2 (algae metagenome) |