| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.A.167.1.1 | Mitoguardin (Mtga) of 525 aas and at least one N-terminal TMS, and possibly one or two more TMSs. It is a regulator of mitochondrial fusion and is required to maintain neuronal homeostasis (Zhang et al. 2016). See TC# 1.R.1 for more details. | Eukaryota |
Metazoa, Arthropoda | MIGA of Drosophila melanogaster (Fruit fly) |
|
8.A.167.1.2 | MitoGuArdin, Fzo-1 or Miga-1, of 499 aas and at least 1 N-terminal TMS plus as many as 5 more TMSs, one next to the N-terminal TMS, and 3 or 4 TMSs at the C-terminus. Fzo1 is involved in mitochondrial membrane fusion and fission (Haeussler et al. 2021). | Eukaryota |
Metazoa, Nematoda | Miga1 of Caenorhabditis elegans |
|
8.A.167.1.3 | Mitoguardin 1 (MITO1 or MITO-1 of 632 aas and 1 N-terminal TMS plus as many as four more TMSs, one next to the N-terminal TMS and as many as 4 C-terminal TMSs. Human mitoguardin 2 is included in TC# 1.R.1.1.1. | Eukaryota |
Metazoa, Chordata | MIGA1 of Homo sapiens |
|
8.A.167.1.4 | Uncharacterized protein of 497 aas with 1 or 2 N-terminal TMSs plus as many as 4 C-terminal TMSs. | Eukaryota |
Metazoa, Chordata | UP of Salmo trutta (river trout) |
|
8.A.167.1.5 | Uncharacterized protein of 435 aas and at least 2 TMSs, N- and C-terminal, but possibly more near the C-terminus. | Eukaryota |
Metazoa, Chordata | UP of Tachysurus fulvidraco (yellow catfish) |