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8.A.189.1.1 AP-4 complex accessory subunit, RUSC2, of 1516 aas and up to 4 TMSs in residues 1000 - 1170. RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery (Guardia et al. 2021).
Accession Number:	Q8N2Y8
Protein Name:	AP-4 complex accessory subunit RUSC2
Length:	1516
Molecular Weight:	161225.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDSPPKLTGE TLIVHHIPLV HCQVPDRQCC GGAGGGGGST RPNPFCPPEL GITQPDQDLG 
61:	QADSLLFSSL HSTPGGTARS IDSTKSRSRD GRGPGAPKRH NPFLLQEGVG EPGLGDLYDD 
121:	SIGDSATQQS FHLHGTGQPN FHLSSFQLPP SGPRVGRPWG TTRSRAGVVE GQEQEPVMTL 
181:	DTQQCGTSHC CRPELEAETM ELDECGGPGG SGSGGGASDT SGFSFDQEWK LSSDESPRNP 
241:	GCSGSGDQHC RCSSTSSQSE AADQSMGYVS DSSCNSSDGV LVTFSTLYNK MHGTPRANLN 
301:	SAPQSCSDSS FCSHSDPGAF YLDLQPSPFE SKMSYESHHP ESGGREGGYG CPHASSPELD 
361:	ANCNSYRPHC EPCPAVADLT ACFQSQARLV VATQNYYKLV TCDLSSQSSP SPAGSSITSC 
421:	SEEHTKISPP PGPGPDPGPS QPSEYYLFQK PEVQPEEQEA VSSSTQAAAA VGPTVLEGQV 
481:	YTNTSPPNLS TGRQRSRSYD RSLQRSPPVR LGSLERMLSC PVRLSEGPAA MAGPGSPPRR 
541:	VTSFAELAKG RKKTGGSGSP PLRVSVGDSS QEFSPIQEAQ QDRGAPLDEG TCCSHSLPPM 
601:	PLGPGMDLLG PDPSPPWSTQ VCQGPHSSEM PPAGLRATGQ GPLAQLMDPG PALPGSPANS 
661:	HTQRDARARA DGGGTESRPV LRYSKEQRPT TLPIQPFVFQ HHFPKQLAKA RALHSLSQLY 
721:	SLSGCSRTQQ PAPLAAPAAQ VSVPAPSGEP QASTPRATGR GARKAGSEPE TSRPSPLGSY 
781:	SPIRSVGPFG PSTDSSASTS CSPPPEQPTA TESLPPWSHS CPSAVRPATS QQPQKEDQKI 
841:	LTLTEYRLHG TGSLPPLGSW RSGLSRAESL ARGGGEGSMA TRPSNANHLS PQALKWREYR 
901:	RKNPLGPPGL SGSLDRRSQE ARLARRNPIF EFPGSLSAAS HLNCRLNGQA VKPLPLTCPD 
961:	FQDPFSLTEK PPAEFCLSPD GSSEAISIDL LQKKGLVKAV NIAVDLIVAH FGTSRDPGVK 
1021:	AKLGNSSVSP NVGHLVLKYL CPAVRAVLED GLKAFVLDVI IGQRKNMPWS VVEASTQLGP 
1081:	STKVLHGLYN KVSQFPELTS HTMRFNAFIL GLLNIRSLEF WFNHLYNHED IIQTHYQPWG 
1141:	FLSAAHTVCP GLFEELLLLL QPLALLPFSL DLLFQHRLLQ SGQQQRQHKE LLRVSQDLLL 
1201:	SAHSTLQLAR ARGQEGPGDV DRAAQGERVK GVGASEGGEE EEEEEETEEV AEAAGGSGRA 
1261:	RWARGGQAGW WYQLMQSSQV YIDGSIEGSR FPRGSSNSSS EKKKGAGGGG PPQAPPPREG 
1321:	VVEGAEACPA SEEALGRERG WPFWMGSPPD SVLAELRRSR EREGPAASPA ENEEGASEPS 
1381:	PGGIKWGHLF GSRKAQREAR PTNRLPSDWL SLDKSMFQLV AQTVGSRREP EPKESLQEPH 
1441:	SPALPSSPPC EVQALCHHLA TGPGQLSFHK GDILRVLGRA GGDWLRCSRG PDSGLVPLAY 
1501:	VTLTPTPSPT PGSSQN

8.A.189.1.1
AP-4 complex accessory subunit, RUSC2, of 1516 aas and up to 4 TMSs in residues 1000 - 1170. RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery (Guardia et al. 2021).

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8.A.189.1.1AP-4 complex accessory subunit, RUSC2, of 1516 aas and up to 4 TMSs in residues 1000 - 1170. RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery (Guardia et al. 2021).

Cross database links:

External Searches:

Analyze:

8.A.189.1.1
AP-4 complex accessory subunit, RUSC2, of 1516 aas and up to 4 TMSs in residues 1000 - 1170. RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery (Guardia et al. 2021).