8.A.43.1.14
Leucine-rich repeat-containing protein 26, LRRC26, of 334 aas. Auxiliary protein of the large-conductance,
voltage and calcium-activated potassium channel (BK alpha). LRRC26 is required for
the conversion of BK alpha channels from a high-voltage to a
low-voltage activated channel type in non-excitable cells. These are
characterized by negative membrane voltages and constant low levels of
calcium (Yan and Aldrich 2010; Yan and Aldrich 2012).
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| Accession Number: | Q2I0M4 |
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| Protein Name: | Leucine-rich repeat-containing protein 26 |
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| Length: | 334 |
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| Molecular Weight: | 34857.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
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1: MRGPSWSRPR PLLLLLLLLS PWPVWAQVSA TASPSGSLGA PDCPEVCTCV PGGLASCSAL
61: SLPAVPPGLS LRLRALLLDH NRVRALPPGA FAGAGALQRL DLRENGLHSV HVRAFWGLGA
121: LQLLDLSANQ LEALAPGTFA PLRALRNLSL AGNRLARLEP AALGALPLLR SLSLQDNELA
181: ALAPGLLGRL PALDALHLRG NPWGCGCALR PLCAWLRRHP LPASEAETVL CVWPGRLTLS
241: PLTAFSDAAF SHCAQPLALR DLAVVYTLGP ASFLVSLASC LALGSGLTAC RARRRRLRTA
301: ALRPPRPPDP NPDPDPHGCA SPADPGSPAA AAQA