8.A.43.1.26
P-granule-associated novel protein 1, PAN1, a leucine-rich LRR-TM protein of 594 aas and 2 TMSs, one at the N-terminus and one near the C-terminus. It regulates diverse developmental processes including larval molting and gonad maturation (Gao et al. 2012; Gissendanner and Kelley 2013). The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling (Xia et al. 2021).
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| Accession Number: | Q9U3A0 |
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| Protein Name: | P-granule-associated novel protein 1 |
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| Length: | 594 |
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| Molecular Weight: | 66371.00 |
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| Species: | Caenorhabditis elegans [6239] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
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| Substrate |
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1: MRSLLSFVLL ALARIAISEE TKSCIDIEKG FKEEFNAHKQ PVCICADNGI FSTVKGFTIE
61: CESASIASVS ENLASLNGTE LGRLTIRDST VNVLPQDLFE NVFAKQVKLE RCGLSTLQPN
121: SFQSLGGSAE LLSLRENRIK KLEKGLFTGL KSLKTLDLAM NKIQEIDVGA FEELKKVEEL
181: LLNENDIRVL KTGTFDGMKN LKKLTLQNCN LEIIQKGAFR GLNSLEQLIL SNNNLENIDW
241: TIFSALKNLR VLDLGSNKIS NVEMKSFPKL EKLVLNNNTI DSMKSIKLKD LPSLVVALFD
301: RNKIESIGDM DMFGLTRSDR IETLSLARNN LSQISPKAFQ HTPNLITLLL QYNQIEELSS
361: HSPSQVRTPF LASLKKLVTL QLSSNNLSVI RSDELPKSLS SLALDHNVIS KIEARALEGM
421: EIKRLYLHSN KLNYLYQGTF DSFSPKSVEA VDVSLNPWVC VCNDPKEWLP RWLEASEEAD
481: VAEGALGCLA IPNCGQKEGS TVMPEEEEVY RSGWITVAAT ILTIVTIVIM VIIAMLYFKD
541: ARYQFPLRGR RSDSDLHKLI ENDPLNIASD SILVVPAMPK RNTGPKKTVR FQNF