8.A.43.2.1
TIR domain-containing adapter molecule 2, TICAM2 (TIRAP3, TIRP, TRAM) of 235 aas and 3 centrally located peaks of minor hydrophobicity that could be TMSs. It functions as sorting adapter in different
signaling pathways to facilitate downstream signaling leading to type I
interferon induction (Huai et al. 2015).
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| Accession Number: | Q86XR7 |
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| Protein Name: | TIR domain-containing adapter molecule 2 |
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| Length: | 235 |
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| Molecular Weight: | 26916.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum1 |
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| Substrate |
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1: MGIGKSKINS CPLSLSWGKR HSVDTSPGYH ESDSKKSEDL SLCNVAEHSN TTEGPTGKQE
61: GAQSVEEMFE EEAEEEVFLK FVILHAEDDT DEALRVQNLL QDDFGIKPGI IFAEMPCGRQ
121: HLQNLDDAVN GSAWTILLLT ENFLRDTWCN FQFYTSLMNS VNRQHKYNSV IPMRPLNNPL
181: PRERTPFALQ TINALEEESR GFPTQVERIF QESVYKTQQT IWKETRNMVQ RQFIA