8.A.60.1.1 TMEM139 protein of 216 aas and 2 N-terminal TMSs. Interacts with and promotes membrane localization of anioin exchanger 1 (AE1; SLC4A1) in human kidney cells (Nuiplot et al. 2015). It may be involved in cellular trafficking of proteins such as SLC4A1 (Nuiplot et al. 2015).
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Accession Number: | Q8IV31 |
Protein Name: | Transmembrane protein 139 |
Length: | 216 |
Molecular Weight: | 23729.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 2 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Single-pass type I membrane protein2 |
Substrate |
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1: MVPMHLLGRL EKPLLLLCCA SFLLGLALLG IKTDITPVAY FFLTLGGFFL FAYLLVRFLE
61: WGLRSQLQSM QTESPGPSGN ARDNEAFEVP VYEEAVVGLE SQCRPQELDQ PPPYSTVVIP
121: PAPEEEQPSH PEGSRRAKLE QRRMASEGSM AQEGSPGRAP INLRLRGPRA VSTAPDLQSL
181: AAVPTLEPLT PPPAYDVCFG HPDDDSVFYE DNWAPP