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8.A.93.2.4 The TM6sf1 protein of 377 aas and 9 or 10 TMSs. Deficiency or overexpression in the liver affects ApoB trafficking and plasma lipid levels, diminished hepatic triglycerides secretion, increased hepatic stestosis and affects atherosclerosis (Ehrhardt et al. 2017).
Accession Number:	Q9BZW5
Protein Name:	Transmembrane 6 superfamily member 1
Length:	370
Molecular Weight:	41636.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	9
Location¹ / Topology² / Orientation³:	Lysosome membrane¹ / Multi-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSASAATGVF VLSLSAIPVT YVFNHLAAQH DSWTIVGVAA LILFLVALLA RVLVKRKPPR 
61:	DPLFYVYAVF GFTSVVNLII GLEQDGIIDG FMTHYLREGE PYLNTAYGHM ICYWDGSAHY 
121:	LMYLVMVAAI AWEETYRTIG LYWVGSIIMS VVVFVPGNIV GKYGTRICPA FFLSIPYTCL 
181:	PVWAGFRIYN QPSENYNYPS KVIQEAQAKD LLRRPFDLML VVCLLLATGF CLFRGLIALD 
241:	CPSELCRLYT QFQEPYLKDP AAYPKIQMLA YMFYSVPYFV TALYGLVVPG CSWMPDITLI 
301:	HAGGLAQAQF SHIGASLHAR TAYVYRVPEE AKILFLALNI AYGVLPQLLA YRCIYKPEFF 
361:	IKTKAEEKVE

8.A.93.2.4
The TM6sf1 protein of 377 aas and 9 or 10 TMSs. Deficiency or overexpression in the liver affects ApoB trafficking and plasma lipid levels, diminished hepatic triglycerides secretion, increased hepatic stestosis and affects atherosclerosis (Ehrhardt et al. 2017).

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8.A.93.2.4The TM6sf1 protein of 377 aas and 9 or 10 TMSs. Deficiency or overexpression in the liver affects ApoB trafficking and plasma lipid levels, diminished hepatic triglycerides secretion, increased hepatic stestosis and affects atherosclerosis (Ehrhardt et al. 2017).

Cross database links:

External Searches:

Analyze:

8.A.93.2.4
The TM6sf1 protein of 377 aas and 9 or 10 TMSs. Deficiency or overexpression in the liver affects ApoB trafficking and plasma lipid levels, diminished hepatic triglycerides secretion, increased hepatic stestosis and affects atherosclerosis (Ehrhardt et al. 2017).