8.A.98.1.10
14-3-3 protein epsilon , 14-3-3ε, of 255 aas and 0 TMSs. It positively regulates phosphorylated protein HSF1 (Q00613; 529 aas, 0 TMSs) nuclear export to the cytoplasm (Wang et al. 2003). A mitochondrial stress-specific form of HSF1 (heat shock factor 1) protects against age-related proteostasis collapse (Williams et al. 2020).
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| Accession Number: | P62258 |
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| Protein Name: | 14-3-3 protein epsilon |
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| Length: | 255 |
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| Molecular Weight: | 29174.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Nucleus1 |
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| Substrate |
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1: MDDREDLVYQ AKLAEQAERY DEMVESMKKV AGMDVELTVE ERNLLSVAYK NVIGARRASW
61: RIISSIEQKE ENKGGEDKLK MIREYRQMVE TELKLICCDI LDVLDKHLIP AANTGESKVF
121: YYKMKGDYHR YLAEFATGND RKEAAENSLV AYKAASDIAM TELPPTHPIR LGLALNFSVF
181: YYEILNSPDR ACRLAKAAFD DAIAELDTLS EESYKDSTLI MQLLRDNLTL WTSDMQGDGE
241: EQNKEALQDV EDENQ