8.A.98.1.11
14-3-3 protein gamma, 14-3-3γ or YWHAG, of 247 aas and 0 TMSs. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (Jin et al. 2006).  The 14-3-3gamma isoform binds to and regulates the localization of endoplasmic reticulum (ER) membrane protein TMCC3 for the reticular network of the ER (Suhda et al. 2023).