8.B.23.2.1
Tx7335 of 63 aas and 1 or 2 TMSs from eastern green mamba snake venom. This toxin activates the potassium channel, KcsA (TC#1.A.1.1.1) (Rivera-Torres et al. 2016). It induces a dose-dependent increase in both open probabilities and mean open times on KcsA in artificial bilayers. The extracellular binding site for Tx7335 is distinct from that of canonical pore-blocker toxins (Rivera-Torres et al. 2016).
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| Accession Number: | C0HJT4 |
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| Protein Name: | Toxin Tx7335 |
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| Length: | 63 |
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| Molecular Weight: | 7344.00 |
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| Species: | Dendroaspis angusticeps (Eastern green mamba) [8618] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: LECHRRGSFI SDGKITCSAK KTFCCKMYEK IFGIYWYGCA KTYTEKNTWN VYSKCCTTNL
61: CNT