| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
8.B.8.1.1 | Discrepin (K+ channel toxin α-KTx15.6) (solution structure solved (2AXK_A); Prochnicka-Chalufour et al., 2006) | Eukaryota |
Metazoa, Arthropoda | Discrepin of Tityus discrepans (P84777) |
|
8.B.8.1.2 | Tx3 toxin; active on A-type K+ and HERG currents (Huys et al., 2004) | Eukaryota |
Metazoa, Arthropoda | Tx3 of Buthus (Mesobuthus) martensii (Q8I0L5) |
|
8.B.8.1.3 | Margatoxin MgTx; Toxin Ce; K+ channel toxin α-KTx of 39 aas. Blocks Kv1.3/KCNA3 voltage-gated potassium channels of human T-lymphocytes but not Ca2+-activated K+ channel | Eukaryota |
Metazoa, Arthropoda | MgTx of Centruroides elegans (bark scorpion) |
|
8.B.8.1.4 | K+ channel toxin 2.11 of 39 aas; also called Toxin Ce4. | Eukaryota |
Metazoa, Arthropoda | Ce4 of Centruroides elegans |
|
8.B.8.1.5 | Matentoxin-1 of 59 aas. | Eukaryota |
Metazoa, Arthropoda | Matentoxin-1 of Mesobuthus martensii |
|
8.B.8.1.6 | Putative K+ channel inhibitor, αKTx30.3; SjKTx51 | Eukaryota |
Metazoa, Arthropoda | KTx51 of Scorpiops jendeki |
|
8.B.8.1.7 | Potassium channel toxin alpha-KTx 6.21; Urotoxin, of 62 aas. Blocker of voltage-gated potassium channels. It has
highest activity on human voltage-gated potassium channel Kv1.2/KCNA2
channels, with an IC50 of 160 pM, whereas its affinity for other channels tested was in the nanomolar range (Luna-Ramírez et al. 2014). | Eukaryota |
Metazoa, Arthropoda | α-KTx 6.21 of Urodacus yaschenkoi (Inland robust scorpion) |
|
8.B.8.1.8 | Potassium channel toxin alpha-KTx 6.11; male-specific potassium channel inhibitor IsTX of 63 aas and 1 N-terminal TMS. Blocks voltage-gated potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3. Causes paralysis to crickets. | Eukaryota |
Metazoa, Arthropoda | ITx 6.11 of Opisthacanthus madagascariensis (Scorpion) |