TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.A.12.1.1









Putative lantibiotic (NAI-107) immunity exporter, MlbJ (247 aas; 6 TMSs)/Q (lipoprotein of 141 aas).  Distinct immunity determinants are: the ABC transporter MlbYZ, and acting cooperatively, the transmembrane protein, MlbJ, and the lipoprotein, MlbQ. NMR structural analysis of MlbQ revealed a hydrophobic surface patch which was proposed to bind the cognate lantibiotic (Pozzi et al. 2015).

Bacteria
Actinomycetota
MlbJQ of Microbispora sp. ATCC PTA-5024
MlbJ (membrane protein of 6 TMSs)
MlbQ (lipoprotein of 141 aas and 1 TMS)
9.A.12.1.2









Uncharacterized protein of 209 aas and 6 TMSs

Bacteria
Actinomycetota
UP of Nocardia brasiliensis
9.A.12.1.3









Uncharacterized pair of homologous proteins of 233 and 251 aas, encoded by adjacent genes, both with 6 TMSs. Adjacent to these two genes are an apparent ABC transporter with TC# 3.A.1.148.4. This family may also be an ABC exporter, but the ATPase is not encided by an adjacent gene and has not been identified. 

Bacteria
Actinomycetota
UPs of Streptosporangium roseum
9.A.12.2.1









Uncharacterized protein of 274 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement.

Bacteria
Actinobacteria
UP of Nocardia amikacinitolerans