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|---|---|
| Accession Number: | P34981 |
| Protein Name: | Thyrotropin-releasing hormone receptor |
| Length: | 398 |
| Molecular Weight: | 45085.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | NONE |
Cross database links:
| Entrez Gene ID: | 7201 |
|---|---|
| Pfam: | PF00001 |
| KEGG: | hsa:7201 hsa:7201 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0004997
F:thyrotropin-releasing hormone receptor activity
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References (16)[1] “Molecular cloning of a functional human thyrotropin-releasing hormone receptor.” Matre V.et.al. 8395824 [2] “Pituitary adenomas of patients with acromegaly express thyrotropin-releasing hormone receptor messenger RNA: cloning and functional expression of the human thyrotropin-releasing hormone receptor gene.” Yamada M.et.al. 8396925 [3] “Cloning and functional characterisation of the human TRH receptor.” Duthie S.M.et.al. 8243797 [4] “Molecular cloning and functional expression of a human thyrotropin-releasing hormone (TRH) receptor gene.” Hinuma S.et.al. 7918619 [5] “Genomic organization and promoter function of the human thyrotropin-releasing hormone receptor gene.” Iwasaki T.et.al. 8703031 [6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [7] “Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptor.” Matre V.et.al. 9886052 [8] “A disulfide bonding interaction role for cysteines in the extracellular domain of the thyrotropin-releasing hormone receptor.” Cook J.V.et.al. 8770906 [9] “Molecular cloning of a functional human thyrotropin-releasing hormone receptor.” Matre V.et.al. 8395824 [10] “Pituitary adenomas of patients with acromegaly express thyrotropin-releasing hormone receptor messenger RNA: cloning and functional expression of the human thyrotropin-releasing hormone receptor gene.” Yamada M.et.al. 8396925 [11] “Cloning and functional characterisation of the human TRH receptor.” Duthie S.M.et.al. 8243797 [12] “Molecular cloning and functional expression of a human thyrotropin-releasing hormone (TRH) receptor gene.” Hinuma S.et.al. 7918619 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MENETVSELN QTQLQPRAVV ALEYQVVTIL LVLIICGLGI VGNIMVVLVV MRTKHMRTPT 61: NCYLVSLAVA DLMVLVAAGL PNITDSIYGS WVYGYVGCLC ITYLQYLGIN ASSCSITAFT 121: IERYIAICHP IKAQFLCTFS RAKKIIIFVW AFTSLYCMLW FFLLDLNIST YKDAIVISCG 181: YKISRNYYSP IYLMDFGVFY VVPMILATVL YGFIARILFL NPIPSDPKEN SKTWKNDSTH 241: QNTNLNVNTS NRCFNSTVSS RKQVTKMLAV VVILFALLWM PYRTLVVVNS FLSSPFQENW 301: FLLFCRICIY LNSAINPVIY NLMSQKFRAA FRKLCNCKQK PTEKPANYSV ALNYSVIKES 361: DHFSTELDDI TVTDTYLSAT KVSFDDTCLA SEVSFSQS