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|---|---|
| Accession Number: | Q15722 |
| Protein Name: | Leukotriene B4 receptor 1 |
| Length: | 352 |
| Molecular Weight: | 37557.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| Entrez Gene ID: | 1241 |
|---|---|
| Pfam: | PF00001 |
| KEGG: | hsa:1241 hsa:1241 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0000166
F:nucleotide binding
GO:0007200
P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0006928
P:cellular component movement
GO:0006955
P:immune response
GO:0006954
P:inflammatory response
GO:0006936
P:muscle contraction
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References (14)[1] “Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.” Akbar G.K.M.et.al. 8702478 [2] “New members of the chemokine receptor gene family.” Raport C.J.et.al. 8558062 [3] “A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.” Yokomizo T.et.al. 9177352 [4] “Cloning of cDNA encoding a putative chemoattractant receptor.” Owman C.S.O.et.al. 8921391 [5] “Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene.” Kato K.et.al. 10934229 [6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [7] “Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.” Gaudreau R.et.al. 12077128 [8] “Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells.” Akbar G.K.M.et.al. 8702478 [9] “New members of the chemokine receptor gene family.” Raport C.J.et.al. 8558062 [10] “A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.” Yokomizo T.et.al. 9177352 [11] “Cloning of cDNA encoding a putative chemoattractant receptor.” Owman C.S.O.et.al. 8921391 [12] “Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene.” Kato K.et.al. 10934229 [13] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [14] “Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.” Gaudreau R.et.al. 12077128
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNTTSSAAPP SLGVEFISLL AIILLSVALA VGLPGNSFVV WSILKRMQKR SVTALMVLNL 61: ALADLAVLLT APFFLHFLAQ GTWSFGLAGC RLCHYVCGVS MYASVLLITA MSLDRSLAVA 121: RPFVSQKLRT KAMARRVLAG IWVLSFLLAT PVLAYRTVVP WKTNMSLCFP RYPSEGHRAF 181: HLIFEAVTGF LLPFLAVVAS YSDIGRRLQA RRFRRSRRTG RLVVLIILTF AAFWLPYHVV 241: NLAEAGRALA GQAAGLGLVG KRLSLARNVL IALAFLSSSV NPVLYACAGG GLLRSAGVGF 301: VAKLLEGTGS EASSTRRGGS LGQTARSGPA ALEPGPSESL TASSPLKLNE LN