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|---|---|
| Accession Number: | Q5T6X5 |
| Protein Name: | G-protein coupled receptor family C group 6 member A |
| Length: | 926 |
| Molecular Weight: | 104753.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | NONE |
Cross database links:
| Entrez Gene ID: | 222545 |
|---|---|
| Pfam: | PF00003 PF01094 PF07562 |
| KEGG: | hsa:222545 hsa:222545 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0004930
F:G-protein coupled receptor activity
GO:0043200
P:response to amino acid stimulus
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References (10)[1] “Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.” Wellendorph P.et.al. 15194188 [2] “The DNA sequence and analysis of human chromosome 6.” Mungall A.J.et.al. 14574404 [3] “Identification of G protein-coupled receptor genes from the human genome sequence.” Takeda S.et.al. 12044878 [4] “Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.” Wellendorph P.et.al. 15576628 [5] “GPRC6A mediates the non-genomic effects of steroids.” Pi M.et.al. 20947496 [6] “Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.” Wellendorph P.et.al. 15194188 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAFLIILITC FVIILATSQP CQTPDDFVAA TSPGHIIIGG LFAIHEKMLS SEDSPRRPQI 61: QECVGFEISV FLQTLAMIHS IEMINNSTLL PGVKLGYEIY DTCTEVTVAM AATLRFLSKF 121: NCSRETVEFK CDYSSYMPRV KAVIGSGYSE ITMAVSRMLN LQLMPQVGYE STAEILSDKI 181: RFPSFLRTVP SDFHQIKAMA HLIQKSGWNW IGIITTDDDY GRLALNTFII QAEANNVCIA 241: FKEVLPAFLS DNTIEVRINR TLKKIILEAQ VNVIVVFLRQ FHVFDLFNKA IEMNINKMWI 301: ASDNWSTATK ITTIPNVKKI GKVVGFAFRR GNISSFHSFL QNLHLLPSDS HKLLHEYAMH 361: LSACAYVKDT DLSQCIFNHS QRTLAYKANK AIERNFVMRN DFLWDYAEPG LIHSIQLAVF 421: ALGYAIRDLC QARDCQNPNA FQPWELLGVL KNVTFTDGWN SFHFDAHGDL NTGYDVVLWK 481: EINGHMTVTK MAEYDLQNDV FIIPDQETKN EFRNLKQIQS KCSKECSPGQ MKKTTRSQHI 541: CCYECQNCPE NHYTNQTDMP HCLLCNNKTH WAPVRSTMCF EKEVEYLNWN DSLAILLLIL 601: SLLGIIFVLV VGIIFTRNLN TPVVKSSGGL RVCYVILLCH FLNFASTSFF IGEPQDFTCK 661: TRQTMFGVSF TLCISCILTK SLKILLAFSF DPKLQKFLKC LYRPILIIFT CTGIQVVICT 721: LWLIFAAPTV EVNVSLPRVI ILECEEGSIL AFGTMLGYIA ILAFICFIFA FKGKYENYNE 781: AKFITFGMLI YFIAWITFIP IYATTFGKYV PAVEIIVILI SNYGILYCTF IPKCYVIICK 841: QEINTKSAFL KMIYSYSSHS VSSIALSPAS LDSMSGNVTM TNPSSSGKSA TWQKSKDLQA 901: QAFAHICREN ATSVSKTLPR KRMSSI