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|---|---|
| Accession Number: | P11279 |
| Protein Name: | Lysosome-associated membrane glycoprotein 1 |
| Length: | 417 |
| Molecular Weight: | 44882.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 2 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Single-pass type I membrane protein2 |
| Substrate | |
Cross database links:
| Entrez Gene ID: | 3916 |
|---|---|
| Pfam: | PF01299 |
| KEGG: | hsa:3916 |
Gene Ontology
GO:0030425
C:dendrite
GO:0010008
C:endosome membrane
GO:0009897
C:external side of plasma membrane
GO:0005887
C:integral to plasma membrane
GO:0042599
C:lamellar body
GO:0005770
C:late endosome
GO:0005765
C:lysosomal membrane
GO:0005764
C:lysosome
GO:0042470
C:melanosome
GO:0005624
C:membrane fraction
GO:0005771
C:multivesicular body
GO:0043025
C:neuronal cell body
GO:0042383
C:sarcolemma
GO:0048102
P:autophagic cell death
GO:0006914
P:autophagy
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References (15)[1] “Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences.” Fukuda M.et.al. 3198605 [2] “The DNA sequence and analysis of human chromosome 13.” Dunham A.et.al. 15057823 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Purification and characterization of human lysosomal membrane glycoproteins.” Mane S.M.et.al. 2912382 [5] “Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000.” Viitala J.et.al. 3131762 [6] “The genes of major lysosomal membrane glycoproteins, lamp-1 and lamp-2. 5'-flanking sequence of lamp-2 gene and comparison of exon organization in two genes.” Sawada R.et.al. 8517882 [7] “Structure of human lysosomal membrane glycoprotein 1. Assignment of disulfide bonds and visualization of its domain arrangement.” Carlsson S.R.et.al. 2584229 [8] “The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones.” Carlsson S.R.et.al. 2243102 [9] “Assignment of O-glycan attachment sites to the hinge-like regions of human lysosomal membrane glycoproteins lamp-1 and lamp-2.” Carlsson S.R.et.al. 8323299 [10] “Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.” Zhang H.et.al. 12754519 [11] “Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.” Liu T.et.al. 16335952 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAAPGSARRP LLLLLLLLLL GLMHCASAAM FMVKNGNGTA CIMANFSAAF SVNYDTKSGP 61: KNMTFDLPSD ATVVLNRSSC GKENTSDPSL VIAFGRGHTL TLNFTRNATR YSVQLMSFVY 121: NLSDTHLFPN ASSKEIKTVE SITDIRADID KKYRCVSGTQ VHMNNVTVTL HDATIQAYLS 181: NSSFSRGETR CEQDRPSPTT APPAPPSPSP SPVPKSPSVD KYNVSGTNGT CLLASMGLQL 241: NLTYERKDNT TVTRLLNINP NKTSASGSCG AHLVTLELHS EGTTVLLFQF GMNASSSRFF 301: LQGIQLNTIL PDARDPAFKA ANGSLRALQA TVGNSYKCNA EEHVRVTKAF SVNIFKVWVQ 361: AFKVEGGQFG SVEECLLDEN SMLIPIAVGG ALAGLVLIVL IAYLVGRKRS HAGYQTI