TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.A.17.1.1









The Pex3/Pex16/Pex19 peroxisomal protein importer (for insertion of integral membranes from the cytosol to the peroxisomal membrane) (Matsuzono and Fujiki, 2006)
Eukaryota
Fungi
Pex3/Pex16/Pex19 of Saccharomyces cerevisiae
Pex3 (P28795)
Pex19 (Q07418)
Pex16 [Not found in S. cerevisiae, but present in many yeast and fungi (e.g., Pex16 from Cryptococcus neoformans, XP_571104)]
9.A.17.1.2









The Pex3/Pex16/Pex19 peroxisomal protein importer is for insertion of integral membranes into the peroxisomal and ER membranes. Monotopic hairpin proteins are inserted into ER membranes. These either remain in the ER as resident ER membrane proteins, or are pinched off from the ER as components of new lipid droplets (Zimmermann et al. 2021).

Eukaryota
Metazoa
Pex3/Pex16/Pex19 of Homo sapiens
Pex3 (P56589)
Pex19 (P40855)
Pex16 (isoform a; Q9BWB9)
Pex16 (isoform b; Q9Y5Y5)
Pex16 (isoform c; EAW68024)
9.A.17.1.3









Pex3/Pex16/Pex19 peroxisomal import complex (for insertion of integral membranes from the cytosol to the peroxisomal membrane) (Hadden et al., 2006; Karnik and Trelease, 2005)
Eukaryota
Viridiplantae
Pex3/Pex16/Pex19 of Arabidopsis thaliana
Pex16 (SSE1; shrunken seed 1) (NP_566053)
Pex3 (NP_566590)
Pex19 (CAD91898)