| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
9.A.80.1.1 | The pecanex-like protein 2, PCNX2 or PCNXL2, of 2137 aas and posslbly 17 TMSs in a 3 (N-terminal) + 14 (residues 840 - 1330) in a 6 + 2 + 6 TMS arrangement. It is a tumor suppressor that regulates the Notch signaling pathway (Naveed et al. 2018). It may play a role in tumorigenesis of colorectal carcinomas, and is characterized by high mutational frequencies and biallelic mutations colorectal tumors. | Eukaryota |
Metazoa, Chordata | PCNX2 of Homo sapiens |
|
9.A.80.1.2 | Protein pecanex isoform X1, PCNX1, of 2538 aas and as many as 19 TMSs in a 2 (N-terminal) + 8 + 8 (residues 1000 - 1580) + possibly 1 (at ~residue 1910) TMS arrangement. | Eukaryota |
Metazoa, Arthropoda | PCNX1 of Contarinia nasturtii (swede midge) |
|
9.A.80.1.3 | Pecanex-like protein, PCNX1, of 1267 aas and possibly 14 TMSs in a 3 or 4 (N-terminal; residues residues 50 - 150) + 8 (residues 200 - 460), and possibly + 2 more TMSs, distant to each other. | Eukaryota |
Metazoa, Chordata | PCNX1 of Hypomesus transpacificus |
|
9.A.80.1.4 | Uncharacterized protein of 1986 aas and 19 TMSs in a 3 (N-terminal; residues 1 - 100) + 8 + 8 (residues 650 - 1180). | Eukaryota |
Metazoa, Rotifera | UP of Rotaria magnacalcarata |
|
9.A.80.1.5 | Pecanex-like protein 4 of 1251 aas and as many as 18 TMSs, 16 of which are included in residues 40 - 720 aas, in pairs of TMSs, plus two possible TMSs nearer the C-terminus. This protein sequence could be a fragment without its N-terminal region. | Eukaryota |
Metazoa, Echinodermata | PCNX4 of Strongylocentrotus purpuratus |