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9.B.12.2.1
Uncharacterized ORF, YqaE, of 52 aas and 2 putative TMSs. The eukaryotic homologues functionally suppress the conditional growth defects in bacterial deletion mutant, demonstrating the conserved cross-kingdom membrane functions by PMP3(i)hs. There is a direct reciprocal relationship between PMP3(i)hs expression and Vm differentials in both prokaryotic and eukaryotic cells. Cumulative with the PMP3(i)hs ubiquitous abundance, their lipid-binding selectivities and membrane protein colocalization, it is a key element in membrane homeostasis (Kwok et al. 2020).

Accession Number:P0AE42
Protein Name:UPF0057 membrane protein yqaE
Length:52
Molecular Weight:5865.00
Species: [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

RefSeq: AP_003239.1    NP_417152.1   
Entrez Gene ID: 947138   
Pfam: PF01679   
BioCyc: EcoCyc:G7396-MONOMER    ECOL168927:B2666-MONOMER   
KEGG: ecj:JW2641    eco:b2666   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (3)

[1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGFWRIVITI ILPPLGVLLG KGFGWAFIIN ILLTLLGYIP GLIHAFWVQT RD