9.B.204. The Prokaryotic 2 TMS domain Protein (Pr2TM) Family
This family is widespread in bacteria and archaea. The 2 TMS domain is referred to as 2TM with Pfam # 13239. It may be involved in cell lysis or peptidoglycan turnover, and thus, could be a holin (TC subclass # 1.E). Some of these proteins have a C-terminal MAS protein import receptor domain (Pfam # 02064).