TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.366.1.1









TMEM117 of 514 aas AND 8 TMSs.  It is involved in the endoplasmic reticulum (ER) stress-induced cell death pathway (Tamaki et al. 2017).

Eukaryota
Metazoa, Chordata
TMEM117 of Homo sapiens
9.B.366.1.2









Uncharacterized protein of 932 aas and about 15 apparent TMSs with an N-terminal domain of 7 or 8 TMSs corrresponding to TMEM117, a C-terminal domain of 6 TMSs corresponding to a small conductance calcium-activated potassium channel protein, SK3 or KCNN3 (see TC#1.A.1.16.7), and 1 (or possibly 2 or 3 TMSs) between these two domains. 

Eukaryota
Oomycota
UP of Aphanomyces stellatus
9.B.366.1.3









Uncharacterized voltage-gated ion channel (VIC) superfamily protein showing 53% identity with 9.B.366.1.2 throughout its length, with a TMEM117 domain in the N-terminus, and VIC superfamily domain in the C-terminus, and a middle domain with at least 1 TMS.

Eukaryota
Oomycota
Two domain protein of Thraustotheca clavata
9.B.366.1.4









Uncharacterized TMEM117 protein of 848 aas and 8 TMSs.

Eukaryota
UP of Aureococcus anophagefferens
9.B.366.1.5









Uncharacterized protein of 1138 aas and 9 TMSs; TMSs 4 - 9 are homologous to TC# 9.B.366.1.1

Eukaryota
Euglenozoa
UP of Trypanosoma theileri
9.B.366.1.6









Uncharacterized protein of 1267 aas and 9 - 11 TMSs.  There are 3 - 5 TMSs in the major portion of the protein followed by a 6 TMS TMEM117 domain at the C-terminus of the protein.

Eukaryota
UP of Symbiodinium microadriaticum