9.B.395. The Uncharacterized Prokaryotic Membrane Protein (UPMP) Family
Members of the UPMP family are integral membrane proteins with 6 or 7 TMSs in a 5+ 1 or 6 + 1 topology, where the N-terminal TMSs are present in a cluster, followed by a hydrophilic region and then a C-terminal TMS. Most protein homologs in the NCBI database are referred to as "hypothetical proteins".