TCDB » SEARCH

« See all members of the family

9.B.411.1.2 Prominin-2 (PROM2) of 834 aas and 6 TMSs in an apparent 1 (N-terminal) +2 + 2 + 1 (C-terminal) TMS arrangement (Jászai et al. 2020). Nuclear export of PROM2 is regulated by CRM1 (TC# 1 I 1.1.3) and affects the sensitivity of ferroptosis in gastric cancer (Zhang et al. 2025).
Accession Number:	Q8N271
Protein Name:	Prominin-2
Length:	834
Molecular Weight:	91883.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Apical cell membrane¹ / Multi-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKHTLALLAP LLGLGLGLAL SQLAAGATDC KFLGPAEHLT FTPAARARWL APRVRAPGLL 
61:	DSLYGTVRRF LSVVQLNPFP SELVKALLNE LASVKVNEVV RYEAGYVVCA VIAGLYLLLV 
121:	PTAGLCFCCC RCHRRCGGRV KTEHKALACE RAALMVFLLL TTLLLLIGVV CAFVTNQRTH 
181:	EQMGPSIEAM PETLLSLWGL VSDVPQELQA VAQQFSLPQE QVSEELDGVG VSIGSAIHTQ 
241:	LRSSVYPLLA AVGSLGQVLQ VSVHHLQTLN ATVVELQAGQ QDLEPAIREH RDRLLELLQE 
301:	ARCQGDCAGA LSWARTLELG ADFSQVPSVD HVLHQLKGVP EANFSSMVQE ENSTFNALPA 
361:	LAAMQTSSVV QELKKAVAQQ PEGVRTLAEG FPGLEAASRW AQALQEVEES SRPYLQEVQR 
421:	YETYRWIVGC VLCSVVLFVV LCNLLGLNLG IWGLSARDDP SHPEAKGEAG ARFLMAGVGL 
481:	SFLFAAPLIL LVFATFLVGG NVQTLVCQSW ENGELFEFAD TPGNLPPSMN LSQLLGLRKN 
541:	ISIHQAYQQC KEGAALWTVL QLNDSYDLEE HLDINQYTNK LRQELQSLKV DTQSLDLLSS 
601:	AARRDLEALQ SSGLQRIHYP DFLVQIQRPV VKTSMEQLAQ ELQGLAQAQD NSVLGQRLQE 
661:	EAQGLRNLHQ EKVVPQQSLV AKLNLSVRAL ESSAPNLQLE TSDVLANVTY LKGELPAWAA 
721:	RILRNVSECF LAREMGYFSQ YVAWVREEVT QRIATCQPLS GALDNSRVIL CDMMADPWNA 
781:	FWFCLAWCTF FLIPSIIFAV KTSKYFRPIR KRLSSTSSEE TQLFHIPRVT SLKL

9.B.411.1.2
Prominin-2 (PROM2) of 834 aas and 6 TMSs in an apparent 1 (N-terminal) +2 + 2 + 1 (C-terminal) TMS arrangement (Jászai et al. 2020). Nuclear export of PROM2 is regulated by CRM1 (TC# 1 I 1.1.3) and affects the sensitivity of ferroptosis in gastric cancer (Zhang et al. 2025).

Cross database links:

External Searches:

Analyze:

9.B.411.1.2Prominin-2 (PROM2) of 834 aas and 6 TMSs in an apparent 1 (N-terminal) +2 + 2 + 1 (C-terminal) TMS arrangement (Jászai et al. 2020). Nuclear export of PROM2 is regulated by CRM1 (TC# 1 I 1.1.3) and affects the sensitivity of ferroptosis in gastric cancer (Zhang et al. 2025).

Cross database links:

External Searches:

Analyze:

9.B.411.1.2
Prominin-2 (PROM2) of 834 aas and 6 TMSs in an apparent 1 (N-terminal) +2 + 2 + 1 (C-terminal) TMS arrangement (Jászai et al. 2020). Nuclear export of PROM2 is regulated by CRM1 (TC# 1 I 1.1.3) and affects the sensitivity of ferroptosis in gastric cancer (Zhang et al. 2025).