TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.62.1.1









The PcoD copper resistance protein of 309 aas and 8 TMSs.

Bacteria
Pseudomonadota
PcoD of E. coli (S52256)
9.B.62.1.2









The CopD copper resistance protein of 310 aas and 8 TMSs.

Bacteria
Pseudomonadota
CopD of Pseudomonas syringae (P12377)
9.B.62.1.3









CopD homologue of 296 aas and 8 TMSs

Bacteria
Pseudomonadota
CopD of Roseomonas cervicalis
9.B.62.1.4









Uncharacterized membrane protein of 290 aas and 8 TMSs, YebZ.

Bacteria
Pseudomonadota
YebZ of E. coli
9.B.62.1.5









Copper (Cu2+) resistance system, CopC (high affinity periplasmic Cu2+ binding protein of 122 aas)/CopD (membrane protein of 291 aas and 8 TMSs) (Wijekoon et al. 2015).  May function with the periplasmic CopA protein and the outer membrane porin, CopB (see TC# 1.B.76.1.6).

Bacteria
Pseudomonadota
CopCD of Pseudomonas fluorescens
9.B.62.1.6









CopD or PcoD of 293 aas and 8 TMSs.  Involved in copper resistance, probably due to copper efflux and plays a role in virulence (Williams et al. 2020).

Bacteria
Pseudomonadota
PcoCD of Acinetobacter baumannii
9.B.62.2.1









Copper resistance protein, CopC of 559 aas and 10 TMS in a 1 + 9 TMS arrangement.

Bacteria
Actinomycetota
CopC of Frankia sp.
9.B.62.2.2









Copper resistance protein CopCD of 551 aas and 9 TMSs

Bacteria
Actinobacteria
CopCD of Frankia symbiont subsp. Datisca glomerata
9.B.62.2.3









Copper resistance D domain protein, CopD of 410 aas and 9 TMSs; may function with the periplasmic CopC copper binding protein (Rehan et al. 2014).
Bacteria
Actinomycetota
CopCD of Frankia sp. strain EuI1c
9.B.62.2.4









CopCD of 659 aas and 8 TMSs.

Archaea
Euryarchaeota
CopCD of Natronomonas pharaonis
9.B.62.2.5









CopD homologue of 311 aas and 8 TMSs.

Bacteria
Pseudomonadota
CopD of Acidiphilium multivorum
9.B.62.2.6









Uncharacterized protein of 157 aas and 4 TMSs.

Bacteria
Pseudomonadota
UP of Tistrella mobilis
9.B.62.3.1









Copper resistance protein, CopD of 736 aas and 16 TMSs in an apparent 8 + 8 TMS arrangement.

Bacteria
Actinomycetota
CopD of Frankia sp.
9.B.62.3.2









This protein has a cytochrome c oxidase caa3-type, assembly factor CtaG-related C-terminal protein domain (~475 - 725 aas) with an N-terminal CopD/PcoD copper sequestering domain (~150 - 375 aas). The protein is of 767 aas with 16 TMSs.

Bacteria
Actinomycetota
CtaG of Frankia sp.
9.B.62.3.3









Putative copper transporter of 249 aas.

Bacteria
Deinococcota
Putative copper transporter of Deinococcus radiodurans
9.B.62.3.4









Putative copper transporter of 176 aas and 4 TMSs.

Bacteria
Actinomycetota
Putative copper transporter of Rhodococcus ruber
9.B.62.3.5









Uncharacterized protein of 223 aas and 5 TMSs

Bacteria
Planctomycetota
UP of Rhodopirellula baltica
9.B.62.3.6









CopD of 321 aas and 9 TMSs.

Bacteria
Actinomycetota
CopD of Mycobacterium smegmatis
9.B.62.3.7









CopD of 270 aas and 7 TMSs.

Bacteria
Actinomycetota
copD of Tsukamurella paurometabola
9.B.62.3.8









Uncharacterized protein of 191 aas and 6 TMSs

Bacteria
Pseudomonadota
UP of Sagittula stellata
9.B.62.3.9









CtiP of 701 aas and 16 TMSs. It has an N-terminal domain resembling the CopD-like copper importer of P. syringae and a cytochrome oxidase maturation protein C-terminal domain resembling CtrG of B. subtilis. This protein is required for the biogenesis of the actinobacterial cytochrome bc1-aa3 supercomplex (Morosov et al. 2018).

Bacteria
Actinomycetota
CtiP of Corynebacterium glutamicum
9.B.62.3.10









CopD/CopC pair of a putative copper transport system. CopD is of 673 aas and 16 putative TMSs; CopC is of 194 aas and 2 TMSs, N- and C-terminal. This system is very similar to that of TC# 9.B.62.3.9 (~50% identical).

Bacteria
Actinomycetota
CopD/CopC of Corynebacterium glutamicum
9.B.62.4.1









Uncharacterized protein of 303 aas and 7 TMSs

Bacteria
Chloroflexota
UP of Caldilinea aerophila
9.B.62.5.1









Uncharacterized protein of 150 aas and 4 TMSs

Bacteria
Aquificota
UP of Hydrogenobacter thermophilus
9.B.62.5.2









Uncharacterized protein of 183 aas and 4 TMSs.

Bacteria
Pseudomonadota
UP of Komagataeibacter hansenii (Gluconacetobacter hansenii)
9.B.62.5.3









Uncharacterized protein of 153 aas and 3 TMSs

Archaea
Euryarchaeota
UP of Halomicrobium mukohataei (Haloarcula mukohataei)