TCDB is operated by the Saier Lab Bioinformatics Group

Protease Inhibitor-like (PI-l) Superfamily

Different families within this superfamilies appear to have different modes of action, and indeed they are not homologous throughout their lengths. However they do show sequence similarity in at least one internal domain.

1.C.50 - The Amyloid β-Protein Peptide (AβPP) Family
8.A.77 - The Sheddase (Sheddase) Family
8.A.180 - The Retinol-binding protein (RBP) Family
8.B.13 - The Sea Anemone Peptide Toxin Class 2 (Kalicludine) Family