Drug/Metabolite Transporter (DMT) Superfamily
DMT family proteins are also found in TC family 1.V.1, one of three protein constituents. They are also called DUF6. These DMT homologous proteins are: 1. 1.V.1.1.1, P46079, 343 aas, 5 TMSs at the N-terminus; 2. 1.V.1.1.2, D5A2X1, 566 aas, 10 TMSs between residues 250 and 560, and 1.V.1.1.3, OJJ22670, 432 aas, 10 TMSs between residues 110 and 420. These proteins are all more similar to each other than to other members of the DMT superfamily. Within superfamily 2.A.7, there are 31 families.
Jack, D.L., N.M. Yang, and M.H. Saier, Jr. (2001). The drug/metabolite transporter superfamily. Eur J Biochem 268: 3620-3639.
Yen, M.R., J.S. Chen, J.L. Marquez, E.I. Sun, and M.H. Saier. (2010). Multidrug resistance: phylogenetic characterization of superfamilies of secondary carriers that include drug exporters. Methods Mol Biol 637: 47-64.
2.A.7 - The Drug/Metabolite Transporter (DMT) Superfamily9.B.120 - The DUF554 (DUF554) Family