Pore-forming Cytotoxin (PfCTx) Superfamily

The PfCTx superfamily consists of proteins, most of them large (between about 500 - 5000 aas), made by a wide range of organisms (a wide range of bacteria and eukaryotes). Family 1.C.41 show very limited sequence similarity with family 1.C.36, of 3 and 5 distantly related families, respectively, and they could be related, but this has not been demonstrated.