1.A.143. The A15.5L Viroporin (A15.5L-VP) Family This family has been examined, first, showing that its characterized member is a small transmembrane protein of 53 aas and 2 TMS (residues 7 - 24 and 30 - 50). Second, it has been shown to have ion channel activity (Basu et al. 2023). Third, its 3-D transmembrane structure has been predicted using alpha-fold.
References:
Basu, K., M. Krugliak, and I.T. Arkin. (2023). Viroporins of Mpox Virus. Int J Mol Sci 24:.
Examples:
TC#	Name	Organismal Type	Example
1.A.143.1.1	*The A15.5L Viroporin of 53 aas and 2 TMSs at residues 7 - 24 and 30 - 50 (Basu et al.* 2023).**		The A15.5L Viroporin of Monkeypox virus

1.A.143.1.2	Uncharacterized protein of 53 aas and 2 TMSs. Putative viroporin.		UP (viroporin) of Finch poxvirus

1.A.143.1.3	MC119L viroporin protein homolog of 53 aas and 2 TMSs.		MC119L viroporin of Molluscum contagijosum virus, subtype 1