1.B.81 The DUF2490 Putative Beta Barrel Porin (DUF2490) Family The DUF2490 family consists of Gram negative bacterial proteins, mostly from Proteobacteria and Bacteroidetes, of about 210 to 280 aas and usually 10 - 12 putative beta strands in a probable beta-barrel as predicted with PRED-TMBB. These proteins show sequence similarity to members of 1.B.35.2 and therefore probably belong to Porin Superfamily I. On this basis, they are assumed to be porins even though there is no direct experimental evidence to prove it.
This family belongs to the Outer Membrane Pore-forming Protein I (OMPP-I) Superfamily .
Examples:
TC#	Name	Organismal Type	Example
1.B.81.1.1	DUF 2490 domain protein of 228 aas	Bacteroidetes	DUF2490 porin of Nonlabens dokdonensis

1.B.81.1.10	Uncharacterized protein of 238 aas		UP of Chryseobacterium indologenes

1.B.81.1.11	DUF2940 protein of 220 aas		UP of Nonlabens dokdonensis (Donghaeana dokdonensis)

1.B.81.1.12	Uncharacterized protein of 246 aas		UP of Mariniradius saccharolyticu

1.B.81.1.13	Uncharacterized protein of 219 aas		UP of Fluviicola taffensis

1.B.81.1.14	Uncharacterized DUF2490 domain-containing protein of 241 aas		UP of Methylosarcina fibrata

1.B.81.1.15	Uncharacterized protein of 234 aas		UP of Sphingomonas sanxanigenens

1.B.81.1.16	Uncharacterized protein of 350 aas, one N-terminal α-TMS and 12 predicted β-TMSs		UP of Nitrosomonas sp. (strain Is79A3)

1.B.81.1.2	Putative porin of 230 aas	Bacteroidetes	PP of Pedobacter saltans

1.B.81.1.3	Putative porin of 221 aas	Proteobacteria	PP of Spingobium indicum

1.B.81.1.4	Putative porin of 228 aas	Proteobacteria	PP of Methylobacterium populi

1.B.81.1.5	Uncharacterized protein of 253 aas		UP of Owenweeksia hongkongensis

1.B.81.1.6	Uncharacterized protein of 244 aas		UP of Cellulophaga algicola

1.B.81.1.7	Uncharacterized protein of 254 aas		UP of Runella slithyformis

1.B.81.1.8	Uncharacterized protein of 244 aas		UP of Haliscomenobacter hydrossis

1.B.81.1.9	Uncharacterized protein of 222 aas		UP of Legionella oakridgensis

Examples:
TC#	Name	Organismal Type	Example
1.B.81.2.1	Uncharacterized protein of 223 aas		*UP of a Chlorobium* species**

1.B.81.2.2	Uncharacterized DUF2490 domain-containing protein of 237 aas with one N-terminal α-TMS and 11 predicted β-TMSs.		UP of Bacterium 336/3