1.E.3 The P2 Holin (P2 Holin) Family See 1.E for a generalized description of Holins.
This family belongs to the Holin III Superfamily .
References:
To, K.H., J. Dewey, J. Weaver, T. Park, and R. Young. (2013). Functional analysis of a class I holin, P2 Y. J. Bacteriol. 195: 1346-1355.
Examples:
TC#	Name	Organismal Type	Example
1.E.3.1.1	*Lysis protein TM (gene Y product), 93aas; 3 TMSs, N out; C in (predicted). This holin has been functionally characterized (To et al.* 2013). It's function is counteracted by the anti-holin, LysA.**	Phage P2	Lysis protein TM (P51773)

1.E.3.1.2	Enterobacterial phage holin family 2 protein, GpY from phage P2	Proteobacterial phage	GpY of phage P2

1.E.3.1.3	*holin protein of E. coli* phage PhiKT**	Proteobacterial phage	Holin of phage PhiKT

1.E.3.1.4	Phage holin of family 2	Proteobacteria	Phage holin of Burkholderia ambifaria

1.E.3.1.5	Putative holin of 96 aas and 3 TMSs	β-Proteobacteria	Putative holin of Achromobacter xylosoxidans

Examples:
TC#	Name	Organismal Type	Example
1.E.3.2.1	Uncharacterized protein	Actinobacteria	Uncharacterized protein of Mycobacterium avium

1.E.3.2.2	Uncharacterized protein (92 aas)	Actinobacteria	Unchazracterized protein of Mycobacterium abscessus

Examples:
TC#	Name	Organismal Type	Example
1.E.3.3.1	Hypothetical protein; putative porin of 89 aas and 3 TMSs.	Crenarchaea	Hypothetical protein of Pyrolobus fumarii